Accuracy of predicting the genetic risk of disease using a genome-wide approach.

BACKGROUND:The prediction of the genetic disease risk of an individual is a powerful public health tool. While predicting risk has been successful in diseases which follow simple Mendelian inheritance, it has proven challenging in complex diseases for which a large number of loci contribute to the g...

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Bibliographic Details
Main Authors: Hans D Daetwyler, Beatriz Villanueva, John A Woolliams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2561058?pdf=render