Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis ProgressionSummary

Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis ProgressionSummary

Background & Aims: Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in mice. However, it is unclear how changes in HSC glutamine metabolism contribut...

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Bibliographic Details
Main Authors: Kuo Du, Satish K. Chitneni, Ayako Suzuki, Ying Wang, Ricardo Henao, Jeongeun Hyun, Richard T. Premont, Susanna Naggie, Cynthia A. Moylan, Mustafa R. Bashir, Manal F. Abdelmalek, Anna Mae Diehl
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Liver Diseases
Biomarker
Metabolomics
Amino Acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19301821

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http://www.sciencedirect.com/science/article/pii/S2352345X19301821

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