Regulation of the human prostacyclin receptor gene by the cholesterol-responsive SREBP1

Regulation of the human prostacyclin receptor gene by the cholesterol-responsive SREBP1

Prostacyclin and its prostacyclin receptor, the I Prostanoid (IP), play essential roles in regulating hemostasis and vascular tone and have been implicated in a range cardio-protective effects but through largely unknown mechanisms. In this study, the influence of cholesterol on human IP [(h)IP] gen...

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Bibliographic Details
Main Authors: Elizebeth C. Turner, B. Therese Kinsella
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Journal of Lipid Research
Subjects:
gene expression
transcription
sterol-response element promoter
sterol-response element binding protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520412556

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520412556

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