Altered serotonin, dopamine and norepinepherine levels in 15q duplication and Angelman syndrome mouse models.

Altered serotonin, dopamine and norepinepherine levels in 15q duplication and Angelman syndrome mouse models.

Childhood neurodevelopmental disorders like Angelman syndrome and autism may be the result of underlying defects in neuronal plasticity and ongoing problems with synaptic signaling. Some of these defects may be due to abnormal monoamine levels in different regions of the brain. Ube3a, a gene that ca...

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Bibliographic Details
Main Authors: M Febin Farook, Michael DeCuypere, Keith Hyland, Toru Takumi, Mark S LeDoux, Lawrence T Reiter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3420863?pdf=render

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