Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae

Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae

In many plants and microorganisms, intracellular proline has a protective role against various stresses, including heat-shock, oxidation and osmolarity. Environmental stresses induce cellular senescence in a variety of eukaryotes. Here we showed that intracellular proline regulates the replicative l...

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Bibliographic Details
Main Authors: Yukio Mukai, Yuka Kamei, Xu Liu, Shan Jiang, Yukiko Sugimoto, Noreen Suliani binti Mat Nanyan, Daisuke Watanabe, Hiroshi Takagi
Format: Article
Language:English
Published: Shared Science Publishers OG 2019-09-01
Series:Microbial Cell
Subjects:
proline
replicative lifespan
stress response
amino acid metabolism
yeast
Online Access:http://microbialcell.com/researcharticles/2019a-mukai-microbial-cell/

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