Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]

Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]

Historically, the 5-year survival rates for patients with stage 4 (metastatic) colorectal cancer were extremely poor (5%); however, with advances in systemic chemotherapy combined with an ability to push the boundaries of surgical resection, survival rates in the range of 25–40% can be achieved. Thi...

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Main Authors: Danielle Collins, Heidi Chua
Format: Article
Language:English
Published: F1000 Research Ltd 2017-04-01
Series:F1000Research
Subjects:
Colon & Rectum
Gastrointestinal Cancers
Liver Failure & Liver Disease
Online Access:https://f1000research.com/articles/6-598/v1
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record_format Article
spelling doaj-28ebcd5f253542a0bc2bd4d900f7d1632020-11-25T03:12:09ZengF1000 Research LtdF1000Research2046-14022017-04-01610.12688/f1000research.10324.111120Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]Danielle Collins0Heidi Chua1Department of Colon and Rectal surgery, Mayo Clinic, Rochester, MN, USADepartment of Colon and Rectal surgery, Mayo Clinic, Rochester, MN, USAHistorically, the 5-year survival rates for patients with stage 4 (metastatic) colorectal cancer were extremely poor (5%); however, with advances in systemic chemotherapy combined with an ability to push the boundaries of surgical resection, survival rates in the range of 25–40% can be achieved. This multimodal approach of combining neo-adjuvant strategies with surgical resection has raised a number of questions regarding the optimal management and timing of surgery. For the purpose of this review, we will focus on the treatment of stage 4 colorectal cancer with synchronous liver metastases.https://f1000research.com/articles/6-598/v1Colon & RectumGastrointestinal CancersLiver Failure & Liver Disease
collection DOAJ
language English
format Article
sources DOAJ
author Danielle Collins
Heidi Chua
spellingShingle Danielle Collins
Heidi Chua
Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
F1000Research
Colon & Rectum
Gastrointestinal Cancers
Liver Failure & Liver Disease
author_facet Danielle Collins
Heidi Chua
author_sort Danielle Collins
title Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
title_short Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
title_full Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
title_fullStr Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
title_full_unstemmed Contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
title_sort contemporary surgical management of synchronous colorectal liver metastases [version 1; referees: 2 approved]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2017-04-01
description Historically, the 5-year survival rates for patients with stage 4 (metastatic) colorectal cancer were extremely poor (5%); however, with advances in systemic chemotherapy combined with an ability to push the boundaries of surgical resection, survival rates in the range of 25–40% can be achieved. This multimodal approach of combining neo-adjuvant strategies with surgical resection has raised a number of questions regarding the optimal management and timing of surgery. For the purpose of this review, we will focus on the treatment of stage 4 colorectal cancer with synchronous liver metastases.
topic Colon & Rectum
Gastrointestinal Cancers
Liver Failure & Liver Disease
url https://f1000research.com/articles/6-598/v1
work_keys_str_mv AT daniellecollins contemporarysurgicalmanagementofsynchronouscolorectallivermetastasesversion1referees2approved
AT heidichua contemporarysurgicalmanagementofsynchronouscolorectallivermetastasesversion1referees2approved
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