The combination of asymmetric hydrogenation of olefins and direct reductive amination

The combination of asymmetric hydrogenation of olefins and direct reductive amination

Asymmetric hydrogenation (AH) and direct reductive amination (DRA) are both frequently utilized in chemical industry. Here, the authors combine these two transformations to efficiently convert in one step prochiral olefins into chiral amino compounds.

Bibliographic Details
Main Authors: Shuai Yuan, Guorui Gao, Lili Wang, Cungang Liu, Lei Wan, Haizhou Huang, Huiling Geng, Mingxin Chang
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14475-x
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spelling doaj-28e77a9dfd754554b58a1a924478fd002021-05-11T08:26:32ZengNature Publishing GroupNature Communications2041-17232020-01-011111710.1038/s41467-020-14475-xThe combination of asymmetric hydrogenation of olefins and direct reductive aminationShuai Yuan0Guorui Gao1Lili Wang2Cungang Liu3Lei Wan4Haizhou Huang5Huiling Geng6Mingxin Chang7Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityCollege of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Shandong Normal UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityAsymmetric hydrogenation (AH) and direct reductive amination (DRA) are both frequently utilized in chemical industry. Here, the authors combine these two transformations to efficiently convert in one step prochiral olefins into chiral amino compounds.https://doi.org/10.1038/s41467-020-14475-x
collection DOAJ
language English
format Article
sources DOAJ
author Shuai Yuan
Guorui Gao
Lili Wang
Cungang Liu
Lei Wan
Haizhou Huang
Huiling Geng
Mingxin Chang
spellingShingle Shuai Yuan
Guorui Gao
Lili Wang
Cungang Liu
Lei Wan
Haizhou Huang
Huiling Geng
Mingxin Chang
The combination of asymmetric hydrogenation of olefins and direct reductive amination
Nature Communications
author_facet Shuai Yuan
Guorui Gao
Lili Wang
Cungang Liu
Lei Wan
Haizhou Huang
Huiling Geng
Mingxin Chang
author_sort Shuai Yuan
title The combination of asymmetric hydrogenation of olefins and direct reductive amination
title_short The combination of asymmetric hydrogenation of olefins and direct reductive amination
title_full The combination of asymmetric hydrogenation of olefins and direct reductive amination
title_fullStr The combination of asymmetric hydrogenation of olefins and direct reductive amination
title_full_unstemmed The combination of asymmetric hydrogenation of olefins and direct reductive amination
title_sort combination of asymmetric hydrogenation of olefins and direct reductive amination
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-01-01
description Asymmetric hydrogenation (AH) and direct reductive amination (DRA) are both frequently utilized in chemical industry. Here, the authors combine these two transformations to efficiently convert in one step prochiral olefins into chiral amino compounds.
url https://doi.org/10.1038/s41467-020-14475-x
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