Discovery of Novel Human Gene Regulatory Modules from Gene Co-expression and Promoter Motif Analysis

Abstract Deciphering gene regulatory networks requires identification of gene expression modules. We describe a novel bottom-up approach to identify gene modules regulated by cis-regulatory motifs from a human gene co-expression network. Target genes of a cis-regulatory motif were identified from th...

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Bibliographic Details
Main Authors: Shisong Ma, Michael Snyder, Savithramma P. Dinesh-Kumar
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05705-2