Amyloid-β peptide alteration of tau exon-10 splicing via the GSK3β-SC35 pathway
Amyloid-beta peptide (Aβ) and Tau protein are the lead constituents in the pathogenesis of Alzheimer's disease (AD). However, their inter-relationship in the disease process remains to be established. Tauopathy refers to a characteristic neurodegenerative process in AD. In tauopathy, Tau accumu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996110002093 |