Development of an Inflammatory CD14+ Dendritic Cell Subset in Humanized Mice

Development of an Inflammatory CD14+ Dendritic Cell Subset in Humanized Mice

Humanized mouse models are attractive experimental models for analyzing the development and functions of human dendritic cells (DCs) in vivo. Although various types of DC subsets, including DC type 3 (DC3s), have been identified in humans, it remains unclear whether humanized mice can reproduce hete...

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Bibliographic Details
Main Authors: Ryutaro Iwabuchi, Keigo Ide, Kazutaka Terahara, Ryota Wagatsuma, Rieko Iwaki, Hiroko Matsunaga, Yasuko Tsunetsugu-Yokota, Haruko Takeyama, Yoshimasa Takahashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
humanized mice
dendritic cell
DC3
CD14
inflammatory response
S100A8
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643040/full

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