DNA elements reducing transcriptional gene silencing revealed by a novel screening strategy.
Transcriptional gene silencing (TGS)--a phenomenon observed in endogenous genes/transgenes in eukaryotes--is a huge hindrance to transgenic technology and occurs mainly when the genes involved share sequence homology in their promoter regions. TGS depends on chromosomal position, suggesting the exis...
Main Authors: | Naoki Kishimoto, Jun-ichi Nagai, Takehito Kinoshita, Keiichiro Ueno, Yuko Ohashi, Ichiro Mitsuhara |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3559876?pdf=render |
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