| Summary: | A descriptive cross-sectional study of 1 819 patients with fever and reactive serology, admitted in "Dr. Antonio María Béguez Caesar" Pediatric Hospital in Santiago de Cuba was carried out through presumptive diagnosis of dengue from January, 2015 to December, 2016, from whom samples of serum were obtained in the Microbiology Department of the above-mentioned institution, which were sent to the laboratory of "Dr. Pedro Kourí" Tropical Medicine Institute in Havana for their processing and possible confirmation. A 54,3 % of positive cases was obtained in the case material, as well as the prevalence of children older than 5 years with 1 451, those coming from Santiago de Cuba municipality were 1 651, those with fever were 847 and those with occurrence of the infection during the trimester October-November were 864.
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