Betulinic Acid–Doxorubicin-Drug Combination Induced Apoptotic Death via ROS Stimulation in a Relapsed AML MOLM-13 Cell Model

Betulinic Acid–Doxorubicin-Drug Combination Induced Apoptotic Death via ROS Stimulation in a Relapsed AML MOLM-13 Cell Model

In this study, cell death regulation and induction in AML cell line from a relapsed MLL-rearranged cell model (MOLM-13) was investigated with doxorubin (Dox) and betulinic acid (BetA), singly and in combination. CyQUANT Direct<sup>®</sup> and Annexin V/propidium iodide double staining we...

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Bibliographic Details
Main Authors: Milan Vu, Nick Kassouf, Sandra Appiah
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
acute myeloid leukaemia
doxorubicin
betulinic acid
apoptosis
drug combination
B-cell lymphoma 2 family of proteins
Online Access:https://www.mdpi.com/2076-3921/10/9/1456

Internet

https://www.mdpi.com/2076-3921/10/9/1456

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