Comparison of antimicrobial efficacy of (between) 0.2% chlorhexidine and herbal mouthwash on salivary Streptococcus mutans: A randomized controlled pilot study

• Main Authors: Swara Shah, Seema Bargale, Bhavna H Dave, Anshula Deshpande, Pratik B Kariya, Anuradha Karri
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2018-01-01
• Series: Contemporary Clinical Dentistry
• Subjects: Chlorhexidine; dental caries; herbal; mouthwash; Terminalia chebula
• Online Access: http://www.contempclindent.org/article.asp?issn=0976-237X;year=2018;volume=9;issue=3;spage=440;epage=445;aulast=Shah

Background: The chemomechanical plaque control measures are helpful in controlling dental plaque and thus caries, especially in pediatric age group. Aim: This study aims to compare effectiveness of herbal mouthrinse containing Terminalia chebula to that of 0.2% chlorhexidine against children's salivary mutans streptococci levels. Settings and Design: A double-blind, randomized, controlled study design will be framed for conducting this study. Methods: A total of 45 participants were randomly categorized in Group 1, Group 2, or Group 3 (control group, experimental group, or negative control). Baseline unstimulated saliva was collected. All the participants were instructed regarding the use of mouthrinse for 2 weeks. After 2 weeks, again unstimulated saliva was collected. After collection, saliva samples were sent for microbiological analysis. Statistical Analysis: The mean colony-forming units (CFU/ml) were determined. Paired t-test, ANOVA test, and post hoc test were applied for statistical analysis. Results: Statistically significant difference in CFU count has been observed in 0.2% chlorhexidine and Oratreat groups at 15 days as compared to baseline (P < 0.001). At 15 days, reduction in CFU count has seen more in Oratreat group as compared to 0.2% chlorhexidine group, and the difference is statistically significant (P < 0.001). Conclusion: 0.2% chlorhexidine and Oratreat mouthwash reduce the salivary Streptococcus mutans count. Oratreat herbal mouthwash has proved to be better as compared to 0.2% chlorhexidine mouthwash.