Platelet APP Processing: Is It a Tool to Explore the Pathophysiology of Alzheimer’s Disease? A Systematic Review

Platelet APP Processing: Is It a Tool to Explore the Pathophysiology of Alzheimer’s Disease? A Systematic Review

The processing of the amyloid precursor protein (APP) is a critical event in the formation of amyloid plaques. Platelets contain most of the enzymatic machinery required for APP processing and correlates of intracerebral abnormalities have been demonstrated in platelets of patients with AD. The goal...

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Bibliographic Details
Main Authors: Manuel Glauco Carbone, Giovanni Pagni, Claudia Tagliarini, Donatella Marazziti, Nunzio Pomara
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Life
Subjects:
Alzheimer’s disease
Aβ cascade
platelet activation
APP processing
Aβ amyloid
Online Access:https://www.mdpi.com/2075-1729/11/8/750

Internet

https://www.mdpi.com/2075-1729/11/8/750

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