PML, SUMOylation and senescence

Since its discovery, 25 years ago, PML has been an enigma. Implicated in the oncogenic PML/RARA fusion, forming elusive intranuclear domains, triggering cell death or senescence, controlled by and perhaps controlling SUMOylation... there are multiple PML-related issues. Here we review the reciprocal...

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Bibliographic Details
Main Authors: Hugues eDe Thé, Lisa eIvanschitz, Morgane eLe Bras
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Oncology
Subjects:
p53
PML
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00171/full