Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

Summary: Obesity-associated metabolic alterations are closely linked to low-grade inflammation in peripheral organs, in which macrophages play a central role. Using genetic labeling of myeloid lineage cells, we show that hypothalamic macrophages normally reside in the perivascular area and circumven...

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Bibliographic Details
Main Authors: Chan Hee Lee, Hyo Jin Kim, Yong-Soo Lee, Gil Myoung Kang, Hyo Sun Lim, Seung-hwan Lee, Do Kyeong Song, Obin Kwon, Injae Hwang, Myeongjoo Son, Kyunghee Byun, Young Hoon Sung, Seyun Kim, Jae Bum Kim, Eun Young Choi, Young-Bum Kim, Keetae Kim, Mi-Na Kweon, Jong-Woo Sohn, Min-Seon Kim
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718315304

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http://www.sciencedirect.com/science/article/pii/S2211124718315304

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