Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis

Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis

Introduction: The signs of Streptococcus pyogenes, group A streptococci (GAS) bacteremia are non-specific and patients can have wide presentations ranging from flu-like symptoms to life-threatening toxic-shock syndrome in just a few hours. Case presentation: We report a case of fulminant S. pyogenes...

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Main Authors: Aarti Chadha, Wafaa Jamal, Abdul R.A. Aziz, Vincent O. Rotimi
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034117302149
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spelling doaj-2886329a4f754bea95a596410629569a2020-11-25T00:48:36ZengElsevierJournal of Infection and Public Health1876-03412018-05-01113434435Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritisAarti Chadha0Wafaa Jamal1Abdul R.A. Aziz2Vincent O. Rotimi3Microbiology Unit, Department of Clinical Laboratory Services, Mubarak Al Kabeer Hospital, KuwaitMicrobiology Unit, Department of Clinical Laboratory Services, Mubarak Al Kabeer Hospital, Kuwait; Department of Microbiology, Faculty of Medicine, Kuwait University, KuwaitDepartment of Medicine, Mubarak Al Kabeer Hospital, Jabriya, KuwaitMicrobiology Unit, Department of Clinical Laboratory Services, Mubarak Al Kabeer Hospital, Kuwait; Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait; Corresponding author at: Clinical Microbiology, Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait.Introduction: The signs of Streptococcus pyogenes, group A streptococci (GAS) bacteremia are non-specific and patients can have wide presentations ranging from flu-like symptoms to life-threatening toxic-shock syndrome in just a few hours. Case presentation: We report a case of fulminant S. pyogenes sepsis in an elderly woman with septic arthritis and remarkable past medical history/risk factors. She was febrile, hypotensive and had a swollen and tender right knee. Multiple blood cultures and the synovial fluid culture yielded S. pyogenes. Despite adequate antimicrobial therapy with penicillin and clindamycin the patient succumbed to her infection within 4 days of presentation in our hospital. Conclusion: GAS remains penicillin sensitive most of the time but prompt appropriate antibiotic therapy is very crucial to survival. Keywords: S. pyogenes, Sepsis, Arthritis, Elderly patienthttp://www.sciencedirect.com/science/article/pii/S1876034117302149
collection DOAJ
language English
format Article
sources DOAJ
author Aarti Chadha
Wafaa Jamal
Abdul R.A. Aziz
Vincent O. Rotimi
spellingShingle Aarti Chadha
Wafaa Jamal
Abdul R.A. Aziz
Vincent O. Rotimi
Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis
Journal of Infection and Public Health
author_facet Aarti Chadha
Wafaa Jamal
Abdul R.A. Aziz
Vincent O. Rotimi
author_sort Aarti Chadha
title Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis
title_short Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis
title_full Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis
title_fullStr Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis
title_full_unstemmed Overwhelming Streptococcus pyogenes sepsis in an elderly patient with septic arthritis
title_sort overwhelming streptococcus pyogenes sepsis in an elderly patient with septic arthritis
publisher Elsevier
series Journal of Infection and Public Health
issn 1876-0341
publishDate 2018-05-01
description Introduction: The signs of Streptococcus pyogenes, group A streptococci (GAS) bacteremia are non-specific and patients can have wide presentations ranging from flu-like symptoms to life-threatening toxic-shock syndrome in just a few hours. Case presentation: We report a case of fulminant S. pyogenes sepsis in an elderly woman with septic arthritis and remarkable past medical history/risk factors. She was febrile, hypotensive and had a swollen and tender right knee. Multiple blood cultures and the synovial fluid culture yielded S. pyogenes. Despite adequate antimicrobial therapy with penicillin and clindamycin the patient succumbed to her infection within 4 days of presentation in our hospital. Conclusion: GAS remains penicillin sensitive most of the time but prompt appropriate antibiotic therapy is very crucial to survival. Keywords: S. pyogenes, Sepsis, Arthritis, Elderly patient
url http://www.sciencedirect.com/science/article/pii/S1876034117302149
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AT abdulraaziz overwhelmingstreptococcuspyogenessepsisinanelderlypatientwithsepticarthritis
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