RIP3 participates in early brain injury after experimental subarachnoid hemorrhage in rats by inducing necroptosis

Necroptosis is a regulated form of necrosis that is mediated by a variety of proteins including tumor necrosis factor-α (TNF-α) and receptor-interacting proteins (RIPs). TNF-α, a critical inflammatory molecule, is one of the initiating signals in the necroptosis pathway, and RIP3 acts as a switch th...

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Bibliographic Details
Main Authors: Shuai Yuan, Zhengquan Yu, Zhuwei Zhang, Juyi Zhang, Peng Zhang, Xiang Li, Haiying Li, Haitao Shen, Gang Chen
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119301196

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