Syngeneic B16F10 Melanoma Causes Cachexia and Impaired Skeletal Muscle Strength and Locomotor Activity in Mice

Syngeneic B16F10 Melanoma Causes Cachexia and Impaired Skeletal Muscle Strength and Locomotor Activity in Mice

Muscle wasting has been emerging as one of the principal components of cancer cachexia, leading to progressive impairment of work capacity. Despite early stages melanomas rarely promotes weight loss, the appearance of metastatic and/or solid tumor melanoma can leads to cachexia development. Here, we...

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Bibliographic Details
Main Authors: Fabrício A. Voltarelli, Fernando T. Frajacomo, Camila de Souza Padilha, Mayra T. J. Testa, Paola S. Cella, Diogo F. Ribeiro, Donizete X. de Oliveira, Luciana C. Veronez, Gabriela S. Bisson, Felipe A. Moura, Rafael Deminice
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Physiology
Subjects:
cancer
melanoma
inflammation
muscle strength
general locomotor activity
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.00715/full

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