Challenges to oligonucleotides-based therapeutics for Duchenne muscular dystrophy

<p>Abstract</p> <p>Antisense oligonucleotides are short nucleic acids designed to bind to specific messenger RNAs in order to modulate splicing patterns or inhibit protein translation. As such, they represent promising therapeutic tools for many disorders and have been actively dev...

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Bibliographic Details
Main Authors: Goyenvalle Aurélie, Davies Kay E
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Skeletal Muscle
Online Access:http://www.skeletalmusclejournal.com/content/1/1/8

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