Forkhead Box Protein C2 Promotes Epithelial-Mesenchymal Transition, Migration and Invasion in Cisplatin-Resistant Human Ovarian Cancer Cell Line (SKOV3/CDDP)

Forkhead Box Protein C2 Promotes Epithelial-Mesenchymal Transition, Migration and Invasion in Cisplatin-Resistant Human Ovarian Cancer Cell Line (SKOV3/CDDP)

Background/Aims: Forkhead Box Protein C2 (FOXC2) has been reported to be overexpressed in a variety of human cancers. However, it is unclear whether FOXC2 regulates epithelial-mesenchymal transition (EMT) in CDDP-resistant ovarian cancer cells. The aim of this study is to investigate the effects of...

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Bibliographic Details
Main Authors: Chanjuan Li, Hongjuan Ding, Jing Tian, Lili Wu, Yun Wang, Yuan Xing, Min Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Forkhead box protein C2
Epithelial-mesenchymal transition
Cisplatin
Chemoresistance
Ovarian cancer
Online Access:http://www.karger.com/Article/FullText/447818

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