Comparative Studies on Retroviral Proteases: Substrate Specificity

Exogenous retroviruses are subclassified into seven genera and include viruses that cause diseases in humans. The viral Gag and Gag-Pro-Pol polyproteins are processed by the retroviral protease in the last stage of replication and inhibitors of the HIV-1 protease are widely used in AIDS therapy. Res...

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Bibliographic Details
Main Author: József Tözsér
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/2/1/147/