Genetically engineered bio-nanoparticles with co-expressed enzyme reporter and recognition element for IgG immunoassay
A bioluminescence-based immunoassay, relying on genetically engineered multifunctional outer membrane vesicles (OMVs, ∼50 nm) with co-expressed enzyme reporter and IgG-binding domain, has been developed for detection of immunoglobulin G (IgG), an important biomacromolecule in humoral immunity. OMVs...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-12-01
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| Series: | Sensors and Actuators Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666053919300037 |