Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1

We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to C...

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Main Authors: Francisco A. B. Speranza, Solange K. Ishii, Luiz C. S. Thuler, Paulo V. Damasco, Raphael Hirata Jr, Ana L. Mattos-Guaraldi, Lucimar G. Milagres
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2012-09-01
Series:Brazilian Journal of Microbiology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300014
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spelling doaj-2839b8824e7043afa67fcf619abb72c92020-11-25T00:07:20ZengSociedade Brasileira de MicrobiologiaBrazilian Journal of Microbiology1517-83821678-44052012-09-0143394695010.1590/S1517-83822012000300014Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1Francisco A. B. SperanzaSolange K. IshiiLuiz C. S. ThulerPaulo V. DamascoRaphael Hirata JrAna L. Mattos-GuaraldiLucimar G. MilagresWe assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300014HIV-1antibody to diphtheria toxinvaccination
collection DOAJ
language English
format Article
sources DOAJ
author Francisco A. B. Speranza
Solange K. Ishii
Luiz C. S. Thuler
Paulo V. Damasco
Raphael Hirata Jr
Ana L. Mattos-Guaraldi
Lucimar G. Milagres
spellingShingle Francisco A. B. Speranza
Solange K. Ishii
Luiz C. S. Thuler
Paulo V. Damasco
Raphael Hirata Jr
Ana L. Mattos-Guaraldi
Lucimar G. Milagres
Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1
Brazilian Journal of Microbiology
HIV-1
antibody to diphtheria toxin
vaccination
author_facet Francisco A. B. Speranza
Solange K. Ishii
Luiz C. S. Thuler
Paulo V. Damasco
Raphael Hirata Jr
Ana L. Mattos-Guaraldi
Lucimar G. Milagres
author_sort Francisco A. B. Speranza
title Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1
title_short Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1
title_full Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1
title_fullStr Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1
title_full_unstemmed Diphtheria Antibodies and T lymphocyte Counts in Patients Infected with HIV-1
title_sort diphtheria antibodies and t lymphocyte counts in patients infected with hiv-1
publisher Sociedade Brasileira de Microbiologia
series Brazilian Journal of Microbiology
issn 1517-8382
1678-4405
publishDate 2012-09-01
description We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination.
topic HIV-1
antibody to diphtheria toxin
vaccination
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000300014
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