Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging

Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging

Herein, we have presented a unique strategy for aqueous synthesis of semiconductor CuInS2 QDs which showed multiple fluorescence. These synthesized CuInS2 QDs were prepared in aqueous media with biocompatible glutathione (GSH), as capping ligand and stabilizer, while the fluorescence and crystallini...

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Main Authors: Anila Arshad, Raheel Akram, Saleem Iqbal, Fozia Batool, Bushra Iqbal, Bilal Khalid, Arif Ullah Khan
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535216301708
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spelling doaj-2833930df8564104abbe630709ab3c332020-11-25T01:11:16ZengElsevierArabian Journal of Chemistry1878-53522019-12-0112848404847Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimagingAnila Arshad0Raheel Akram1Saleem Iqbal2Fozia Batool3Bushra Iqbal4Bilal Khalid5Arif Ullah Khan6Beijing University of Chemical Technology, ChinaBeijing University of Chemical Technology, China; Corresponding author.Beijing University of Chemical Technology, ChinaUniversity of Sargodha, PakistanBeijing University of Chemical Technology, ChinaTsinghua University, ChinaBeijing University of Chemical Technology, ChinaHerein, we have presented a unique strategy for aqueous synthesis of semiconductor CuInS2 QDs which showed multiple fluorescence. These synthesized CuInS2 QDs were prepared in aqueous media with biocompatible glutathione (GSH), as capping ligand and stabilizer, while the fluorescence and crystallinity were controlled by varying the reaction time. The investigation of various other experimental parameters including precursor’s concentration, effect of pH, and stability of QDs has also been carried out. These QDs were characterized by XRD, TEM, and FT-IR. Meanwhile, optical properties of as synthesized QDs were also investigated by fluorescence spectroscopy. Furthermore, the synthesized QDs were also less cytotoxic and maintained remarkable cell viability up to 100 μg/mL. When bioconjugated with Arginyl-glycyl-aspartic acid (RGD) moiety, the obtained CuInS2-RGD QDs have shown higher biocompatibility and good bioimaging performance. Keywords: Aqueous synthesis, CuInS2, Quantum dots, Fluorescence, Bioimaginghttp://www.sciencedirect.com/science/article/pii/S1878535216301708
collection DOAJ
language English
format Article
sources DOAJ
author Anila Arshad
Raheel Akram
Saleem Iqbal
Fozia Batool
Bushra Iqbal
Bilal Khalid
Arif Ullah Khan
spellingShingle Anila Arshad
Raheel Akram
Saleem Iqbal
Fozia Batool
Bushra Iqbal
Bilal Khalid
Arif Ullah Khan
Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging
Arabian Journal of Chemistry
author_facet Anila Arshad
Raheel Akram
Saleem Iqbal
Fozia Batool
Bushra Iqbal
Bilal Khalid
Arif Ullah Khan
author_sort Anila Arshad
title Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging
title_short Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging
title_full Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging
title_fullStr Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging
title_full_unstemmed Aqueous synthesis of tunable fluorescent, semiconductor CuInS2 quantum dots for bioimaging
title_sort aqueous synthesis of tunable fluorescent, semiconductor cuins2 quantum dots for bioimaging
publisher Elsevier
series Arabian Journal of Chemistry
issn 1878-5352
publishDate 2019-12-01
description Herein, we have presented a unique strategy for aqueous synthesis of semiconductor CuInS2 QDs which showed multiple fluorescence. These synthesized CuInS2 QDs were prepared in aqueous media with biocompatible glutathione (GSH), as capping ligand and stabilizer, while the fluorescence and crystallinity were controlled by varying the reaction time. The investigation of various other experimental parameters including precursor’s concentration, effect of pH, and stability of QDs has also been carried out. These QDs were characterized by XRD, TEM, and FT-IR. Meanwhile, optical properties of as synthesized QDs were also investigated by fluorescence spectroscopy. Furthermore, the synthesized QDs were also less cytotoxic and maintained remarkable cell viability up to 100 μg/mL. When bioconjugated with Arginyl-glycyl-aspartic acid (RGD) moiety, the obtained CuInS2-RGD QDs have shown higher biocompatibility and good bioimaging performance. Keywords: Aqueous synthesis, CuInS2, Quantum dots, Fluorescence, Bioimaging
url http://www.sciencedirect.com/science/article/pii/S1878535216301708
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