Sequential unusual site metastases in renal cell cancer: Saga of repeated tumor implantation and prolonged survival without systemic therapy

• Main Authors: Siddharth Yadav, Rishi Nayyar, Amlesh Seth
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2016-01-01
• Series: Urology Annals
• Subjects: Bladder renal cell cancer; metachronous metastasis; metastatectomy in renal cell cancer; renal cell cancer with rare site metastasis; ureteric renal cell cancer
• Online Access: http://www.urologyannals.com/article.asp?issn=0974-7796;year=2016;volume=8;issue=1;spage=102;epage=104;aulast=Yadav

Renal cell cancer (RCC) is known to produce metastasis to unusual sites both synchronously and metachronously several years after the primary treatment. We report a rare case of RCC with three different, sequential, and each time isolated rare site metastasis to ureteric stump, surgical site, and urinary bladder over a period of 6 years after radical nephrectomy. At each recurrence, metastasectomy was carried out and no systemic therapy was administered. Eleven years after radical nephrectomy and 5 years after last resection, the patient remains disease free. Multiple recurrences can occur in RCC and complete surgical resection results in disease free survival.