Decidual NR2F2-Expressing CD4+ T Cells Promote TH2 Transcriptional Program During Early Pregnancy

Decidual NR2F2-Expressing CD4+ T Cells Promote TH2 Transcriptional Program During Early Pregnancy

A unique immunotolerant microenvironment with Th2 bias in the decidua provides an essential security for successful pregnancy. The disorganized maternal-fetal immune tolerance contributes to more than 50% of unexplained recurrent spontaneous abortion (RSA). How the Th2 bias is developed at the mater...

Full description

Bibliographic Details
Main Authors: Yikong Lin, Di Zhang, Yangyang Li, Yunyun Li, Bin Li, Meirong Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
CD4+T cell
NR2F2
GATA-3
pregnancy
maternal-fetal immune tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.670777/full

Similar Items

Similar Items