The murine angiotensin II-induced abdominal aortic aneurysm model: rupture risk and inflammatory progression patterns

The murine angiotensin II-induced abdominal aortic aneurysm model: rupture risk and inflammatory progression patterns

An abdominal aortic aneurysm (AAA) is an enlargement of the greatest artery in the body defined as an increase in diameter of 1.5-fold. AAAs are common in the elderly population and thousands die each year from their complications. The most commonly used mouse model to study the pathogenesis of AAA...

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Bibliographic Details
Main Authors: Richard Y Cao, Timothy St. Amand, Matthew D Ford, Ugo Piomelli, Colin D Funk
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-07-01
Series:Frontiers in Pharmacology
Subjects:
Inflammation
macrophage
Pathogenesis
ultrasound
mouse model
Apolipoprotein E
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2010.00009/full

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