Highly parallel and efficient single cell mRNA sequencing with paired picoliter chambers
Single-cell RNA-seq can reveal accurate and precise cell types and states. Here the authors present an scRNA-seq platform, Paired-seq, which uses differential flow resistance to achieve 95% cell utilisation efficiency for improved cell-free RNA removal and gene detection.
Bibliographic Details
| Main Authors: |
Mingxia Zhang,
Yuan Zou,
Xing Xu,
Xuebing Zhang,
Mingxuan Gao,
Jia Song,
Peifeng Huang,
Qin Chen,
Zhi Zhu,
Wei Lin,
Richard N. Zare,
Chaoyong Yang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-15765-0
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