A centriolar FGR1 oncogene partner-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes

A centriolar FGR1 oncogene partner-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes

Proteins of the FGR1 oncogene partner (or FOP) family are found at microtubule organizing centres (MTOCs) including, in flagellate eukaryotes, the centriole or flagellar basal body from which the axoneme extends. We report conservation of FOP family proteins, TbFOPL and TbOFD1, in the evolutionarily...

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Bibliographic Details
Main Authors: Jane Harmer, Katie Towers, Max Addison, Sue Vaughan, Michael L. Ginger, Paul G. McKean
Format: Article
Language:English
Published: The Royal Society 2018-07-01
Series:Open Biology
Subjects:
basal body
ciliogenesis
fgr1 oncogene partner
trypanosoma brucei
cell morphogenesis
paraflagellar rod
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170218

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