Late de novo minimal change disease in a renal allograft

Among the causes of the nephrotic syndrome in renal allografts, minimal change disease is a rarity with only few cases described in the medical literature. Most cases described have occurred early in the post-transplant course. There is no established treatment for the condition but prognosis is fav...

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Bibliographic Details
Main Authors: Madhan Krishan, Temple-Camp Cynric
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Subjects:
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2009;volume=20;issue=2;spage=266;epage=269;aulast=Madhan
Description
Summary:Among the causes of the nephrotic syndrome in renal allografts, minimal change disease is a rarity with only few cases described in the medical literature. Most cases described have occurred early in the post-transplant course. There is no established treatment for the condition but prognosis is favorable. We describe a case of minimal change disease that developed 8 years after a successful transplantation of a renal allograft in a middle-aged woman. The nephrotic syndrome was accompanied by deterioration of allograft function. Treatment with mycophenolate mofetil was successful in inducing remission and stabilizing allograft function.
ISSN:1319-2442