Identification of Alkaloids from Corydalis yanhusuo W. T. Wang as Dopamine D1 Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay

Identification of Alkaloids from Corydalis yanhusuo W. T. Wang as Dopamine D1 Receptor Antagonists by Using CRE-Luciferase Reporter Gene Assay

Corydalis yanhusuo W. T. Wang (C. yanhusuo) has been traditionally used for drug addiction and pain relief in China. In our previous study, we showed that the extract of C. yanhusuo blocks dopamine receptors, demonstrating that its pharmacological activities are mostly due to the antagonistic effect...

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Bibliographic Details
Main Authors: Lehao Wu, Weiyue Zhang, Xin Qiu, Chaoran Wang, Yanfang Liu, Zhiwei Wang, Yang Yu, Richard D. Ye, Yan Zhang
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
Corydalis yanhusuo W. T. Wang
luciferase reporter gene assay
D1 receptor
FLIPR
Online Access:http://www.mdpi.com/1420-3049/23/10/2585

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