Non-enzymatic primer extension with strand displacement

Non-enzymatic primer extension with strand displacement

Non-enzymatic RNA self-replication is integral to the emergence of the ‘RNA World’. Despite considerable progress in non-enzymatic template copying, demonstrating a full replication cycle remains challenging due to the difficulty of separating the strands of the product duplex. Here, we report a pre...

Full description

Bibliographic Details
Main Authors: Lijun Zhou, Seohyun Chris Kim, Katherine H Ho, Derek K O'Flaherty, Constantin Giurgiu, Tom H Wright, Jack W Szostak
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-11-01
Series:eLife
Subjects:
synthesis RNA
synthesis 3'-NP-DNA
Online Access:https://elifesciences.org/articles/51888

Internet

https://elifesciences.org/articles/51888

Similar Items