ANTISYNTHETASE SYNDROME IS THE MOST SEVERE SUBTYPE OF POLYMYOSITIS/DERMATOMYOSITIS:DESCRIPTION OF CASES

ANTISYNTHETASE SYNDROME IS THE MOST SEVERE SUBTYPE OF POLYMYOSITIS/DERMATOMYOSITIS:DESCRIPTION OF CASES

Polymyositis (PM) and dermatomyositis (DM) are autoimmune skeletal muscle diseases of unknown etiology, which are referred to as systemic connective tissue diseases and united under the common term Tidiopathic inflammatory myopathiesy. The most severe subtype of PM/DM is the antisynthetase syndrome...

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Bibliographic Details
Main Authors: Olga Alekseyevna Antelava, G M Tarasova, E G Sazhina, Yu A Olyunin, R M Balabanova, E L Nasonov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2009-12-01
Series:Современная ревматология
Subjects:
polymyositis
dermatomyositis
antisynthetase syndrome
Online Access:https://mrj.ima-press.net/mrj/article/view/259
Description
Summary:Polymyositis (PM) and dermatomyositis (DM) are autoimmune skeletal muscle diseases of unknown etiology, which are referred to as systemic connective tissue diseases and united under the common term Tidiopathic inflammatory myopathiesy. The most severe subtype of PM/DM is the antisynthetase syndrome that is characterized by a certain sympathocomplex, including interstitial lung lesion that is one of the most common visceral changes. Of interest are the specific features of the antisynthetase syndrome, its onset, the course and pulmonary manifestations of fibrosing alveolitis, unlike the classical course of PM/DM. Two clinical cases of the antisynthetase syndrome are given.
ISSN:1996-7012
2310-158X

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