The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways

The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways

Ras analog in brain (Rab) proteins are small guanosine triphosphatases (GTPases) that belong to the Ras-like GTPase superfamily, and they can regulate vesicle trafficking. Rab proteins alternate between an activated (GTP-bound) state and an inactivated (GDP-bound) state. Early endosome marker Rab5 G...

Full description

Bibliographic Details
Main Authors:	Wanqiong Yuan, Chunli Song
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	Biochemistry Research International
Online Access:	http://dx.doi.org/10.1155/2020/4186308

Similar Items

Rab-domain dynamics in endocytic membrane trafficking
by: Rink, Jochen C.
Published: (2005)

The Role of Rab Proteins in Neuronal Cells and in the Trafficking of Neurotrophin Receptors
by: Cecilia Bucci, et al.
Published: (2014-10-01)

Cytokine Secretion in Macrophages: SNAREs, Rabs and Membrane Trafficking.
by: Rachael Zoe Murray, et al.
Published: (2014-10-01)

Rab GTPases: Central Coordinators of Membrane Trafficking in Cancer
by: Hongyuan Jin, et al.
Published: (2021-06-01)

Multitasking Rab Proteins in Autophagy and Membrane Trafficking: A Focus on Rab33b
by: Niamh E. Morgan, et al.
Published: (2019-08-01)

Intracellular Signaling and Trafficking in Cancer: Role of Rab5-GTPase in Migration and Invasion of Breast Cells
by: Porther, Nicole
Published: (2015)

Regulation of PDGF receptor trafficking and signalling by the RabGAP function of p85α
Published: (2015)

Structural Basis of Membrane Trafficking by Rab Family Small G Protein
by: Hyun Ho Park
Published: (2013-04-01)

Rab5 and Rab11 maintain hematopoietic homeostasis by restricting multiple signaling pathways in Drosophila
by: Shichao Yu, et al.
Published: (2021-02-01)

Membrane Trafficking of Death Receptors: Implications on Signalling
by: Wulf Schneider-Brachert, et al.
Published: (2013-07-01)

Apical Trafficking Pathways of Influenza A Virus HA and NA via Rab17- and Rab23-Positive Compartments
by: Ryota Sato, et al.
Published: (2019-08-01)

Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations
by: Pilar Rivero-Ríos, et al.
Published: (2020-07-01)

VipD of Legionella pneumophila targets activated Rab5 and Rab22 to interfere with endosomal trafficking in macrophages.
by: Bonsu Ku, et al.
Published: (2012-01-01)

Structure/function analysis of hRme-6, a rab5 GEF that integrates trafficking and signaling
by: Zhu, Zhou
Published: (2017)

The trypanosome Rab-related proteins RabX1 and RabX2 play no role in intracellular trafficking but may be involved in fly infectivity.
by: Senthil Kumar A Natesan, et al.
Published: (2009-09-01)

Vesicle Trafficking: A Rab Family Profile
by: Harris, Kathryn P., et al.
Published: (2014)

A role of Rab29 in the integrity of the trans-Golgi network and retrograde trafficking of mannose-6-phosphate receptor.
by: Shicong Wang, et al.
Published: (2014-01-01)

Phosphoinositides, Major Actors in Membrane Trafficking and Lipid Signaling Pathways
by: Johan-Owen De Craene, et al.
Published: (2017-03-01)

Large Rab GTPases: Novel Membrane Trafficking Regulators with a Calcium Sensor and Functional Domains
by: Takayuki Tsukuba, et al.
Published: (2021-07-01)

RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking
by: Yasuko Kitagishi, et al.
Published: (2013-03-01)

Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
by: Shirley Tremel, et al.
Published: (2021-03-01)

Rab GTPases and the Autophagy Pathway: Bacterial Targets for a Suitable Biogenesis and Trafficking of Their Own Vacuoles
by: María Milagros López de Armentia, et al.
Published: (2016-03-01)

CSN6 and Rab34 Are Involved in Androgen Receptor Trafficking in Mouse Testicular Sertoli Cells
by: Qiong Deng, et al.
Published: (2018-07-01)

The role of calpain-myosin 9-Rab7b pathway in mediating the expression of Toll-like receptor 4 in platelets: a novel mechanism involved in α-granules trafficking.
by: Jui-Chi Tsai, et al.
Published: (2014-01-01)

Rab8 Mediates TRPV4 Vesicle Trafficking to the Plasma Membrane in HGF-Stimulated MDCK Cells
by: Haws, Hillary Jean
Published: (2016)

Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling.
by: Jian Heng, et al.
Published: (2020-04-01)

The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2.
by: Mark N Adams, et al.
Published: (2011-01-01)

RAB11-Mediated Trafficking and Human Cancers: An Updated Review
by: Elsi Ferro, et al.
Published: (2021-01-01)

Crosstalk and Integration of Membrane Trafficking Pathways
Published: (2012)

Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa.
by: Ramesh C Nayak, et al.
Published: (2013-01-01)

Rab11 regulates trafficking of trans-sialidase to the plasma membrane through the contractile vacuole complex of Trypanosoma cruzi.
by: Sayantanee Niyogi, et al.
Published: (2014-06-01)

Arf6 and Rab22 mediate T cell conjugate formation by regulating clathrin-independent endosomal membrane trafficking
by: Johnson, Debra L., et al.
Published: (2017)

Roles of Myosin-Mediated Membrane Trafficking in TGF-β Signaling
by: Chih-Ling Chung, et al.
Published: (2019-08-01)

Multiple roles for membrane-associated protein trafficking and signaling in gravitropism
by: Allison Karen Strohm, et al.
Published: (2012-12-01)

Prenylated Rab acceptor 1 promotes the intracellular trafficking and NF-kappaB signaling of Epstein-Barr virus-encoded latent membrane protein 1
by: Hao-Ping Liu, et al.
Published: (2006)

Epidermal growth factor-mediated Rab25 pathway regulates integrin β1 trafficking in colon cancer
by: Kyung Sook Hong, et al.
Published: (2018-03-01)

Chlamydia trachomatis CT229 Subverts Rab GTPase-Dependent CCV Trafficking Pathways to Promote Chlamydial Infection
by: Robert Faris, et al.
Published: (2019-03-01)

Narrowing the Rab GAP: identifying a role for TBC-2 in endosomal trafficking in «Caenorhabditis elegans»
by: Chotard, Laetitia
Published: (2011)

Evolution of Membrane Signaling and Trafficking in Plants
by: Markus eGeisler
Published: (2013-03-01)

Small Rab GTPases in Intracellular Vesicle Trafficking: The Case of Rab3A/Raphillin-3A Complex in the Kidney
by: Olga Martinez-Arroyo, et al.
Published: (2021-07-01)