NOS2 deficiency has no influence on the radiosensitivity of the hematopoietic system

NOS2 deficiency has no influence on the radiosensitivity of the hematopoietic system

Abstract Objective Previous studies have shown that inhibition of inducible NO synthase (NOS2 or iNOS) with an inhibitor can selectively protect several normal tissues against radiation during radiotherapy. However, the role of NOS2 in ionizing radiation (IR)-induced bone marrow (BM) suppression is...

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Bibliographic Details
Main Authors: Chengcheng Li, Yi Luo, Lijian Shao, Aimin Meng, Daohong Zhou
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Cell & Bioscience
Subjects:
Hematopoietic stem cell
Ionizing radiation
NOS2−/−
Online Access:http://link.springer.com/article/10.1186/s13578-018-0228-0

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