Epigenetic Changes during Hepatic Stellate Cell Activation.

Hepatic stellate cells (HSC), which can participate in liver regeneration and fibrogenesis, have recently been identified as liver-resident mesenchymal stem cells. During their activation HSC adopt a myofibroblast-like phenotype accompanied by profound changes in the gene expression profile. DNA met...

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Bibliographic Details
Main Authors: Silke Götze, Eva C Schumacher, Claus Kordes, Dieter Häussinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466775?pdf=render