SCISSOR: a framework for identifying structural changes in RNA transcripts

SCISSOR: a framework for identifying structural changes in RNA transcripts

Many computational tools identify mRNA variations by analyzing the transformed RNA-seq data such as collapsed reads. Here, the authors report a computational method which uses shape changes in the RNA-seq coverage profile to discover changes in mRNA expression and alternative splicing.

Bibliographic Details
Main Authors: Hyo Young Choi, Heejoon Jo, Xiaobei Zhao, Katherine A. Hoadley, Scott Newman, Jeremiah Holt, Michele C. Hayward, Michael I. Love, J. S. Marron, D. Neil Hayes
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20593-3

Internet

https://doi.org/10.1038/s41467-020-20593-3

Similar Items