The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review

The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review

Abstract Background Neurotensin, originally isolated in 1973 has both endocrine and neuromodulator activity and acts through its three main receptors. Their role in promoting tumour cell proliferation, migration, DNA synthesis has been studied in a wide range of cancers. Expression of Neurotensin an...

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Bibliographic Details
Main Authors: Stella Nikolaou, Shengyang Qiu, Francesca Fiorentino, Constantinos Simillis, Shahnawaz Rasheed, Paris Tekkis, Christos Kontovounisios
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Cell Communication and Signaling
Subjects:
Neurotensin
Neurotensin receptors
Cancer
Online Access:http://link.springer.com/article/10.1186/s12964-020-00569-y

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