Optimization of the Biosynthesis of B-Ring <i>Ortho</i>-Hydroxy Lated Flavonoids Using the 4-Hydroxyphenylacetate 3-Hydroxylase Complex (HpaBC) of <i>Escherichia coli</i>

Optimization of the Biosynthesis of B-Ring <i>Ortho</i>-Hydroxy Lated Flavonoids Using the 4-Hydroxyphenylacetate 3-Hydroxylase Complex (HpaBC) of <i>Escherichia coli</i>

Flavonoids are important plant metabolites that exhibit a wide range of physiological and pharmaceutical functions. Because of their wide biological activities, such as anti-inflammatory, antioxidant, antiaging and anticancer, they have been widely used in foods, nutraceutical and pharmaceuticals in...

Full description

Bibliographic Details
Main Authors:	Longji Wang, Xiubing Ma, Haixiang Ruan, Yang Chen, Liping Gao, Ting Lei, Yan Li, Lin Gui, Lina Guo, Tao Xia, Yunsheng Wang
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	Molecules
Subjects:	B-ring <i>ortho</i>-hydroxylation <i>Escherichia coli</i> flavonoids 4-hydroxyphenylacetate 3-hydroxylase biosynthesis
Online Access:	https://www.mdpi.com/1420-3049/26/10/2919

Similar Items

A single amino acid substitution in aromatic hydroxylase (HpaB) of Escherichia coli alters substrate specificity of the structural isomers of hydroxyphenylacetate
by: Hanseol Kim, et al.
Published: (2020-05-01)

Adjusting <i>Ortho</i>-Cycloalkyl Ring Size in a Cycloheptyl-Fused <i>N</i>,<i>N</i>,<i>N</i>-Iron Catalyst as Means to Control Catalytic Activity and Polyethylene Properties
by: Mingyang Han, et al.
Published: (2020-09-01)

Molecular and Enzymatic Characterization of Flavonoid 3′-Hydroxylase of <i>Malus</i> × <i>domestica</i>
by: Julia Weissensteiner, et al.
Published: (2021-09-01)

Influence of Electronic Environment on the Radiative Efficiency of 9-Phenyl-9<i>H</i>-carbazole-Based <i>ortho</i>-Carboranyl Luminophores
by: Seok Ho Lee, et al.
Published: (2021-03-01)

The Oxidation of Equol by Tyrosinase Produces a Unique Di-<i>ortho</i>-Quinone: Possible Implications for Melanocyte Toxicity
by: Hitomi Tanaka, et al.
Published: (2021-08-01)

Characterization and Transcriptional Regulation of <i>n</i>-Alkane Hydroxylase Gene Cluster of <i>Rhodococcus jostii</i> RHA1
by: Namiko Gibu, et al.
Published: (2019-10-01)

Half-Preparative Scale Synthesis of (<i>S</i>)-1-Phenylethane-1,2-Diol as a Result of 2-Phenylethanol Hydroxylation with <i>Aspergillus niger</i> (IAFB 2301) Assistance
by: Beata Szmigiel-Merena, et al.
Published: (2020-06-01)

Triazolium Salt Organocatalysis: Mechanistic Evaluation of Unusual <i>Ortho</i>-Substituent Effects on Deprotonation
by: Peter Quinn, et al.
Published: (2021-08-01)

The Effect of the <i>ortho</i> Nitro Group in the Solvolysis of Benzyl and Benzoyl Halides
by: Kyoung-Ho Park, et al.
Published: (2019-08-01)

De Novo Biosynthesis of <i>p</i>-Coumaric Acid in <i>E. coli</i> with a <i>trans</i>-Cinnamic Acid 4-Hydroxylase from the Amaryllidaceae Plant <i>Lycoris aurea</i>
by: Yikui Li, et al.
Published: (2018-12-01)

Polyphenol-Hydroxylating Tyrosinase Activity under Acidic pH Enables Efficient Synthesis of Plant Catechols and Gallols
by: Hanbit Song, et al.
Published: (2021-09-01)

The Effect of Intramolecular Hydrogen Bond Type on the Gas-Phase Deprotonation of <i>ortho</i>-Substituted Benzenesulfonic Acids. A Density Functional Theory Study
by: Nina I. Giricheva, et al.
Published: (2020-12-01)

Identification of <i>Toxoplasma Gondii</i> Tyrosine Hydroxylase (TH) Activity and Molecular Immunoprotection against Toxoplasmosis
by: Zhenchao Zhang, et al.
Published: (2020-04-01)

Evaluation of Phage Therapy in the Context of <i>Enterococcus faecalis</i> and Its Associated Diseases
by: Andrei S. Bolocan, et al.
Published: (2019-04-01)

The Role of Tyramine β-Hydroxylase in Density Dependent Immunityof Oriental Armyworm (<i>Mythmina separata</i>) Larva
by: Hailong Kong, et al.
Published: (2019-03-01)

Three Melanin Pathway Genes, <i>TH</i>, <i>yellow</i>, and <i>aaNAT</i>, Regulate Pigmentation in the Twin-Spotted Assassin Bug, <i>Platymeris biguttatus</i> (Linnaeus)
by: Yinqiao Zhang, et al.
Published: (2019-06-01)

Further Studies on the 3-Ketosteroid 9α-Hydroxylase of <i>Rhodococcus ruber</i> Chol-4, a Rieske Oxygenase of the Steroid Degradation Pathway
by: Sara Baldanta, et al.
Published: (2021-05-01)

Isolation, Bioactivity, and Production of ortho-Hydroxydaidzein and ortho-Hydroxygenistein
by: Te-Sheng Chang
Published: (2014-04-01)

Molecular and Potential Regulatory Mechanisms of Melanin Synthesis in <i>Harmonia axyridis</i>
by: Da Xiao, et al.
Published: (2020-03-01)

Characterization of enzymatic properties of two novel enzymes, 3,4-dihydroxyphenylacetate dioxygenase and 4-hydroxyphenylacetate 3-hydroxylase, from Sulfobacillus acidophilus TPY
by: Wenbin Guo, et al.
Published: (2019-02-01)

Structural Aspects of the <i>Ortho</i> Chloro- and Fluoro- Substituted Benzoic Acids: Implications on Chemical Properties
by: Gulce Ogruc Ildiz, et al.
Published: (2020-10-01)

Degradation Potential of the Nonylphenol Monooxygenase of <i>Sphingomonas</i> sp. NP5 for Bisphenols and Their Structural Analogs
by: Masahiro Takeo, et al.
Published: (2020-02-01)

Engineering the Steroid Hydroxylating System from <i>Cochliobolus lunatus</i> in <i>Mycolicibacterium smegmatis</i>
by: Carmen Felpeto-Santero, et al.
Published: (2021-07-01)

One-Pot Synthesis of <i>B</i>-Aryl Carboranes with Sensitive Functional Groups Using Sequential Cobalt- and Palladium-Catalyzed Reactions
by: Sergey A. Anufriev, et al.
Published: (2020-11-01)

A Novel Pinkish-White Flower Color Variant Is Caused by a New Allele of Flower Color Gene <i>W1</i> in Wild Soybean (<i>Glycine soja</i>)
by: Jagadeesh Sundaramoorthy, et al.
Published: (2021-05-01)

Characterization and Transcriptome Analysis of a Long-Chain <i>n</i>-Alkane-Degrading Strain <i>Acinetobacter pittii</i> SW-1
by: Weina Kong, et al.
Published: (2021-06-01)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
by: Matthew E Cockman, et al.
Published: (2019-09-01)

Role of Some Food-Grade Synthesized Flavonoids on the Control of Ochratoxin A in <i>Aspergillus carbonarius</i>
by: Alessandra Ricelli, et al.
Published: (2019-07-01)

<i>RgC3H</i> Involves in the Biosynthesis of Allelopathic Phenolic Acids and Alters Their Release Amount in <i>Rehmannia glutinosa</i> Roots
by: Yan Hui Yang, et al.
Published: (2020-04-01)

Fluorometric Optimized Determination of Total Glutathione in Erythrocytes
by: Antonio Francioso, et al.
Published: (2021-06-01)

<i>Lactobacillus crispatus</i> BC1 Biosurfactant Delivered by Hyalurosomes: An Advanced Strategy to Counteract <i>Candida</i> Biofilm
by: Angela Abruzzo, et al.
Published: (2021-01-01)

ATP and NADPH engineering of Escherichia coli to improve the production of 4-hydroxyphenylacetic acid using CRISPRi
by: Yu-Ping Shen, et al.
Published: (2021-04-01)

<i>Lactobacillus crispatus</i> BC1 Biosurfactant Counteracts the Infectivity of <i>Chlamydia trachomatis</i> Elementary Bodies
by: Claudio Foschi, et al.
Published: (2021-04-01)

<i>Aspergillus flavus</i> Exploits Maize Kernels Using an “Orphan” Secondary Metabolite Cluster
by: Ludovica Antiga, et al.
Published: (2020-11-01)

<i>Diaphorina citri</i> Genome Possesses a Complete Melatonin Biosynthesis Pathway Differentially Expressed under the Influence of the Phytopathogenic Bacterium, <i>Candidatus</i> Liberibacter asiaticus
by: Yasser Nehela, et al.
Published: (2021-04-01)

A New Strategy for the Synthesis of Hydroxyl Terminated Polystyrene-<i>b</i>-Polybutadiene-<i>b</i>-Polystyrene Triblock Copolymer with High Cis-1, 4 Content
by: Xin Min, et al.
Published: (2019-04-01)

New Butenolides and Cyclopentenones from Saline Soil-Derived Fungus <i>Aspergillus Sclerotiorum</i>
by: Li-Ying Ma, et al.
Published: (2019-07-01)

The Synthesis and Utility of Metal-Nitrosophenolato Compounds—Highlighting the Baudisch Reaction
by: Alexander J. Nicholls, et al.
Published: (2019-11-01)

Development of <i>Atropa belladonna</i> L. Plants with High-Yield Hyoscyamine and without Its Derivatives Using the CRISPR/Cas9 System
by: Lingjiang Zeng, et al.
Published: (2021-02-01)

Overexpression of a Pak Choi Gene, <i>BcAS2</i>, Causes Leaf Curvature in <i>Arabidopsis thaliana</i>
by: Ye Lin, et al.
Published: (2021-01-01)

Cannot write session to /tmp/vufind_sessions/sess_22gqss7h755han9vk86hv09v47