Pluripotent stem cell-derived skeletal muscle fibers preferentially express myosin heavy-chain isoforms associated with slow and oxidative muscles

Pluripotent stem cell-derived skeletal muscle fibers preferentially express myosin heavy-chain isoforms associated with slow and oxidative muscles

Abstract Background Skeletal muscle function is essential for health, and it depends on the proper activity of myofibers and their innervating motor neurons. Each adult muscle is composed of different types of myofibers with distinct contractile and metabolic characteristics. The proper balance of m...

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Bibliographic Details
Main Authors: Tania Incitti, Alessandro Magli, Asher Jenkins, Karena Lin, Ami Yamamoto, Rita C. R. Perlingeiro
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Skeletal Muscle
Subjects:
Pluripotent stem cells (PSC)
Skeletal myogenesis
Myofibers
Fiber types
Fast
Slow
Online Access:http://link.springer.com/article/10.1186/s13395-020-00234-5

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