Comparison of inbred mouse substrains reveals segregation of maladaptive fear phenotypes

Comparison of inbred mouse substrains reveals segregation of maladaptive fear phenotypes

Maladaptive fear, such as fear that is persistent or easily generalized to a nonthreatening stimuli, is associated with anxiety-related disorders in humans. In the laboratory, maladaptive fear can be modeled in rodents using Pavlovian fear conditioning. Recently, an inbred mouse strain known as 129...

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Bibliographic Details
Main Authors:	Stephanie J Temme, Ryan Z Bell, Reciton ePahumi, Geoffrey G Murphy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-08-01
Series:	Frontiers in Behavioral Neuroscience
Subjects:	extinction generalization context discrimination inbred mouse strains conditioned fear maladaptive fear
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00282/full

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