Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells

Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells

Abstract Background Astrocytes respond to central nervous system (CNS) injury and disease by transforming to a reactive astrogliosis cell state that can contribute to either CNS dysfunction or repair. Neuroinflammation is a powerful driver of a harmful A1 astrogliosis phenotype associated with in vi...

Full description

Bibliographic Details
Main Authors: Qiong Zhou, Coralie Viollet, Anastasia Efthymiou, Guzal Khayrullina, Kasey E. Moritz, Matthew D. Wilkerson, Gauthaman Sukumar, Clifton L. Dalgard, Martin L. Doughty
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Neuroinflammation
Subjects:
Human induced pluripotent stem cell
Astrocyte
RNA sequencing
Glutamate uptake
Phagocytosis
Online Access:http://link.springer.com/article/10.1186/s12974-019-1553-x

Internet

http://link.springer.com/article/10.1186/s12974-019-1553-x

Similar Items