Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections

Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of...

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Main Authors: Bogdan Stefan Vasile, Alexandra Catalina Birca, Mihaela Carmen Musat, Alina Maria Holban
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/13/7/1682
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spelling doaj-27babe10a68c483eb9173ad0ed1aa16f2020-11-25T03:49:28ZengMDPI AGMaterials1996-19442020-04-01131682168210.3390/ma13071682Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound InfectionsBogdan Stefan Vasile0Alexandra Catalina Birca1Mihaela Carmen Musat2Alina Maria Holban3National Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, Splaiul Independenţei Street, No. 313, 060042 Bucharest, RomaniaNational Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, Splaiul Independenţei Street, No. 313, 060042 Bucharest, RomaniaFaculty of Engineering in Foreign Language, University Politehnica of Bucharest, Romania, Splaiul Independenţei Street, No. 313, 060042 Bucharest, RomaniaDepartment of Microbiology and Immunology, Faculty of Biology, University of Bucharest, Aleea Portocalelor, No. 1-3, 050663 Bucharest, RomaniaInfection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management.https://www.mdpi.com/1996-1944/13/7/1682dip coatingsilver nanoparticlesessential oilsantimicrobial
collection DOAJ
language English
format Article
sources DOAJ
author Bogdan Stefan Vasile
Alexandra Catalina Birca
Mihaela Carmen Musat
Alina Maria Holban
spellingShingle Bogdan Stefan Vasile
Alexandra Catalina Birca
Mihaela Carmen Musat
Alina Maria Holban
Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
Materials
dip coating
silver nanoparticles
essential oils
antimicrobial
author_facet Bogdan Stefan Vasile
Alexandra Catalina Birca
Mihaela Carmen Musat
Alina Maria Holban
author_sort Bogdan Stefan Vasile
title Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_short Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_full Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_fullStr Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_full_unstemmed Wound Dressings Coated with Silver Nanoparticles and Essential Oils for The Management of Wound Infections
title_sort wound dressings coated with silver nanoparticles and essential oils for the management of wound infections
publisher MDPI AG
series Materials
issn 1996-1944
publishDate 2020-04-01
description Infection represents one of the major risk factors in persistent and difficult to treat wounds. This study focuses on developing antimicrobial wound dressings coated with silver nanoparticles, sodium alginate and different essential oils, to avoid wound infection and biofilm formation. The design of the wound dressings was done by the dip coating method. The characteristics of the developed materials were analysed by physicochemical (FT-IR, XRD, SEM, TEM) and biological (antimicrobial tests) approaches. The results demonstrated uniform silver nanoparticle formation on the substrate, and the developed nanomodified dressings were proven to have increased antimicrobial and antibiofilm potential. The developed wound dressings based on silver nanoparticles, sodium alginate and essential oils have real potential in treating infections, and can be investigated as an efficient alternative to antibiotics and topical preparations for wound management.
topic dip coating
silver nanoparticles
essential oils
antimicrobial
url https://www.mdpi.com/1996-1944/13/7/1682
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