FOXO3 Promotes Quiescence in Adult Muscle Stem Cells during the Process of Self-Renewal
Skeletal muscle stem cells, or “satellite cells” (SCs), are required for the regeneration of damaged muscle tissue. Although SCs self-renew during regeneration, the mechanisms that govern SC re-entry into quiescence remain elusive. We show that FOXO3, a member of the forkhead family of transcription...
Main Authors: | Suchitra D. Gopinath, Ashley E. Webb, Anne Brunet, Thomas A. Rando |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-04-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221367111400054X |
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