Transient degradation of NF-κB proteins in macrophages after interaction with mast cell granules

Transient degradation of NF-κB proteins in macrophages after interaction with mast cell granules

The exposure of the macrophage cell line, J774 to mast cell granules (MCG) led to the form ation of altered nuclear transcription factor proteins (NFκBx), which had faster electrophoretic mobility than the p50 homodimer of NF-κB, but retained comparable DNA binding capacity. Antibodies to N-terminal...

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Bibliographic Details
Main Authors: Noriko Ito, Yuai Li, Tsuneo Suzuki, Daniel J. Stechschulte, Kottarappat N. Dileepan
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Mediators of Inflammation
Subjects:
Macrophages
Mast cells
Mast cell granules
NF-κB
Nitric oxide synthase
TNF-α.
Online Access:http://dx.doi.org/10.1080/09629359890776

Internet

http://dx.doi.org/10.1080/09629359890776

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