EGFR soluble isoforms and their transcripts are expressed in meningiomas.

The EGFR (epidermal growth factor receptor) is involved in the oncogenesis of many tumors. In addition to the full-length EGFR (isoform a), normal and tumor cells produce soluble EGFR isoforms (sEGFR) that lack the intracellular domain. sEGFR isoforms b, c and d are encoded by EGFR variants 2 (v2),...

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Bibliographic Details
Main Authors: Angélique Guillaudeau, Karine Durand, Barbara Bessette, Alain Chaunavel, Isabelle Pommepuy, Fabrice Projetti, Sandrine Robert, François Caire, Hélène Rabinovitch-Chable, François Labrousse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22623992/pdf/?tool=EBI