Interaction of age and mechanical stability on bone defect healing: an early transcriptional analysis of fracture hematoma in rat.

Among other stressors, age and mechanical constraints significantly influence regeneration cascades in bone healing. Here, our aim was to identify genes and, through their functional annotation, related biological processes that are influenced by an interaction between the effects of mechanical fixa...

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Bibliographic Details
Main Authors: Andrea Ode, Georg N Duda, Sven Geissler, Stephan Pauly, Jan-Erik Ode, Carsten Perka, Patrick Strube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4154721?pdf=render