CHARACTERISATION AND STUDY OF 1- [2- (2-BENZOYLPHENOXY) ETHYL] -6-METHYLURACIL MECHANISM OF ACTION

CHARACTERISATION AND STUDY OF 1- [2- (2-BENZOYLPHENOXY) ETHYL] -6-METHYLURACIL MECHANISM OF ACTION

The aim of the study is to identify 1-[2-(2-benzoylphenoxy) ethyl]-6-methyluracil using various methods of analysis, as well as to study its action mechanism against wild-type and mutant forms of HIV-1 reverse transcriptase (RT).Materials and methods. To characterize the structure of the test substa...

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Bibliographic Details
Main Authors: E. A. Jain (Korsakova), D. V. Demchenko, A. A. Ozerov, M. N. Makarova, V. G. Makarov, V. Yu. Balabanyan
Format: Article
Language:Russian
Published: Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical University 2021-07-01
Series:Farmaciâ i Farmakologiâ (Pâtigorsk)
Subjects:
1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil
identification
x-ray structural analysis
thermal analysis
elemental analysis
uv spectroscopy
ir spectroscopy
nmr spectroscopy
action mechanism
hiv-1 reverse transcriptase
Online Access:https://www.pharmpharm.ru/jour/article/view/829

Internet

https://www.pharmpharm.ru/jour/article/view/829

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